In 2022, we celebrate the 500th anniversary of printing in the Grand Duchy of Lithuania. In 1522, the Ruthenian printer Francysk Skaryna issued the “Little Traveller’s Book”, a publication that marked the beginning of crucially important changes in the culture of Lithuania. The Grand Duchy of Lithuania became a member of the community of European countries that printed books, i. e. mastered the most modern means and methods of information and communication. Far from accidental, this development was caused by several reasons and was promoted by the most prominent Lithuanian statesmen, scholars, and people of culture belonging to several religious denominations. And this is what this virtual exhibition is about.